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Changes to Accrued Cease-Use Liability (Detail) - USD ($) $ in Thousands		3 Months Ended
		Mar. 31, 2017	Mar. 31, 2016
Commitments and Contingencies Disclosure [Abstract]
Beginning balance		$ 853	$ 1,983
Change in estimate	[1]	0	(830)
Payments		(66)	(110)
Ending balance		$ 787	$ 1,043
[1] Change in estimate was offset by an increase in deferred rent of approximately $246,000 during the first quarter of 2016.

X

- Definition

Amount of liability recorded for the net present value estimated difference between 1) the income to be generated under the Sublease and future subleases, and 2) the Lease obligation over the remaining term of the Lease for the space that is occupied by the subtenant.

+ References

No definition available.

+ Details

Name:	nbix_CeaseUseLiability
Namespace Prefix:	nbix_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

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- Definition

Payments during the period associated with the Cease-use Liability.

+ References

No definition available.

+ Details

Name:	nbix_CeaseUseLiabilityPayment
Namespace Prefix:	nbix_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

X

- Definition

Change In Estimate On Cease Use Liability

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No definition available.

+ Details

Name:	nbix_ChangeInEstimateOnCeaseUseLiability
Namespace Prefix:	nbix_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

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- References

No definition available.

+ Details

Name:	us-gaap_CommitmentsAndContingenciesDisclosureAbstract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration