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Summary of Quarterly Results of Operations (Detail) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Quarterly Financial Information Disclosure [Abstract]                      
Revenues $ 94,517 $ 60,774 $ 6,335 $ 0 $ 0 $ 0 $ 0 $ 15,000 $ 161,626 $ 15,000 $ 19,769
Operating expenses 82,683 66,769 63,603 79,932 46,251 38,436 41,828 35,857 292,987 162,372 113,971
Net (loss) income $ 6,894 $ (11,125) $ (59,985) $ (78,326) $ (44,659) $ (36,887) $ (40,280) $ (19,264) $ (142,542) $ (141,090) $ (88,929)
Net (loss) income per share:                      
Basic $ 0.08 $ (0.13) $ (0.68) $ (0.90)         $ (1.62) $ (1.63) $ (1.05)
Diluted $ 0.07 $ (0.13) $ (0.68) $ (0.90)         $ (1.62) (1.63) $ (1.05)
Net loss per share:                      
Basic and Diluted         $ (0.51) $ (0.43) $ (0.46) $ (0.22)   $ (1.63)  
Shares used in the calculation of net (loss) income per share:                      
Basic 88,665 88,325 88,063 87,283         88,089 86,713 84,496
Diluted 92,659 88,325 88,063 87,283         88,089 86,713 84,496
Shares used in the calculation of net loss per share:                      
Basic and Diluted         86,874 86,784 86,694 86,497   86,713