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Income Taxes - Additional Information (Detail) - USD ($)
 12 Months Ended
Jan. 01, 2018
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Taxes [Line Items]        
Deferred tax assets   $ 362,700,000 $ 463,500,000  
Deferred tax liabilities   31,800,000 0  
Research and development tax credit carry forwards   $ 47,500,000 $ 38,800,000  
Corporate tax rate   35.00% 35.00% 35.00%
Deferred tax assets, valuation allowance   $ 330,900,000 $ 463,500,000  
Percentage of uncertain tax positions likelihood of being sustained   50.00%    
Accrual interest or penalties   $ 0 0  
Increases related to current year tax positions   3,291,000 $ 2,211,000 $ 2,584,000
Unrecognized tax benefits that would affect effective tax rate   30,700,000    
Subsequent Event        
Income Taxes [Line Items]        
Corporate tax rate 21.00%      
Federal        
Income Taxes [Line Items]        
Operating loss carry forward, net   $ 978,700,000    
Operating loss carry forward beginning expiration year   2021    
Research and development tax credit carry forwards   $ 48,200,000    
Alternative Minimum Tax credit carry forwards   $ 100,000    
Federal | R&D        
Income Taxes [Line Items]        
Tax credit carry forwards beginning expiration year   2018    
State and Local Jurisdiction        
Income Taxes [Line Items]        
Operating loss carry forward, net   $ 535,300,000    
Research and development tax credit carry forwards   $ 34,600,000    
State and Local Jurisdiction | California        
Income Taxes [Line Items]        
Operating loss carry forward beginning expiration year   2018    
State and Local Jurisdiction | Other States        
Income Taxes [Line Items]        
Operating loss carry forward beginning expiration year   2027