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Provision for Income Taxes on Earnings Subject to Income Taxes Differs from Statutory Federal Rate (Detail) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Income Tax Disclosure [Abstract] |  |  |
Federal income taxes at 21% for 2018 and 35% for 2017 and 2016 | $ 4,587 | $ (49,889) | $ (49,383)
State income tax, net of federal benefit | 361 | (4,013) | 2
Tax effect on non-deductible expenses | 446 | 433 | (321)
Share-based compensation expense | (9,778) | (19,589) | (5,077)
Officer compensation | 915 | 2,163 | 0
Change in tax rate | (198) | 154,415 | 0
Expired tax attributes | 13,874 | 2,998 | 6,708
Research credits | (13,526) | (5,596) | (5,554)
Change in valuation allowance | 4,306 | (79,966) | 53,414
Other | (257) | (956) | 211
Income Tax Expense (Benefit), Total | $ 730 | $ 0 | $ 0

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- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Subparagraph (h) -URI http://asc.fasb.org/extlink&oid=115929826&loc=d3e8736-108599 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08(h)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 20 -Section 45 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=109238882&loc=d3e38679-109324 + Details
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