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Organization and Summary of Significant Accounting Policies - Additional Information (Detail) $ in Thousands, shares in Millions |  | 12 Months Ended
--- | --- | ---
May 02, 2017 USD ($) | Dec. 31, 2018 USD ($) Site Customer shares | Dec. 31, 2017 USD ($) Customer | Dec. 31, 2016 USD ($)
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Convertible senior notes principal amount |  | $ 517,500 | $ 517,500 |
Depreciation |  | 4,000 | 2,400 | $ 1,500
Restricted cash |  | 5,477 | 4,500 |
ASU 2016-18 |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Restricted cash |  | 5,500 | $ 4,500 |
ASU 2016-02 (Topic 842) |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Right-of-use (ROU) assets |  | 49,000 |  |
Lease liabilities |  | 69,000 |  |
Derecognition of deferred rent for certain lease incentives received |  | 20,000 |  |
ASU 2016-02 (Topic 842) | Recognition of Deferred Gain on Sale of Real Estate |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Deferred gain on sale of real estate as cumulative-effect adjustment to equity |  | $ 8,000 |  |
Performance-based RSUs |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Share equivalents excluded from computation of earnings per share | shares |  | 0.3 |  |
ESPP |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Purchase period |  | 6 months |  |
Customer Concentration Risk | Sales Revenue, Goods, Net |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Number of customers | Customer |  | 3 | 3 |
Percentage of product revenue |  | 93.00% | 93.00% |
Customer Concentration Risk | Accounts Receivable |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Number of customers | Customer |  | 3 | 3 |
Ingrezza |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Number of separate commercial production sites | Site |  | 2 |  |
Advertising costs |  | $ 20,500 | $ 10,100 |
Minimum |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Average estimated useful life of equipment |  | 3 years |  |
Requisite service period of award |  | 3 years |  |
Maximum |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Average estimated useful life of equipment |  | 7 years |  |
Requisite service period of award |  | 4 years |  |
2.25% Convertible Senior Notes due 2024 |  |  |  |
Organization And Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Convertible senior notes |  | 7 years |  |
Fair value of convertible senior note as percentage of principal amount |  | 119.00% | 128.00% |
Convertible senior notes principal amount | $ 517,500 |  |  |
Convertible senior notes interest percentage | 2.25% |  |  |
Convertible senior notes interest rate | 2.25% |  |  |
Convertible senior notes convertible latest date |  | May 15, 2024 |  |
Share equivalents excluded from computation of earnings per share | shares |  | 6.8 |  |

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