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INCOME TAXES (Tables) | 12 Months Ended
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Dec. 31, 2018
Income Tax Disclosure [Abstract] |
Components of Income Tax Expense for Continuing Operations | The components of the income tax expense for continuing operations are as follows:
(in thousands) |  | 2018 |  |  | 2017 |  |  | 2016 |
Current: |  |  |  |  |  |  |  |  |  |  |  |
Federal |  | $ | (100 | ) |  | $ | — |  |  | $ | — |
State |  |  | 830 |  |  |  | — |  |  |  | — |
Total income tax expense |  | $ | 730 |  |  | $ | — |  |  | $ | — |
Provision for Income Taxes on Earnings Subject to Income Taxes Differs from Statutory Federal Rate | The provision for income taxes on earnings subject to income taxes differs from the statutory federal rate at December 31, 2018, 2017 and 2016, due to the following:
(in thousands) |  | 2018 |  |  | 2017 |  |  | 2016 |
Federal income taxes at 21% for 2018 and 35% for 2017 and 2016 |  | $ | 4,587 |  |  | $ | (49,889 | ) |  | $ | (49,383 | )
State income tax, net of federal benefit |  |  | 361 |  |  |  | (4,013 | ) |  |  | 2 |
Tax effect on non-deductible expenses |  |  | 446 |  |  |  | 433 |  |  |  | (321 | )
Share-based compensation expense |  |  | (9,778 | ) |  |  | (19,589 | ) |  |  | (5,077 | )
Officer compensation |  |  | 915 |  |  |  | 2,163 |  |  |  | — |
Change in tax rate |  |  | (198 | ) |  |  | 154,415 |  |  |  | — |
Expired tax attributes |  |  | 13,874 |  |  |  | 2,998 |  |  |  | 6,708 |
Research credits |  |  | (13,526 | ) |  |  | (5,596 | ) |  |  | (5,554 | )
Change in valuation allowance |  |  | 4,306 |  |  |  | (79,966 | ) |  |  | 53,414 |
Other |  |  | (257 | ) |  |  | (956 | ) |  |  | 211 |
|  | $ | 730 |  |  | $ | — |  |  | $ | — |
Components of Deferred Tax Assets | Amounts are shown as of December 31 as of each respective year:
(in thousands) |  | 2018 |  |  | 2017 |
Deferred tax assets: |  |  |  |  |  |  |  |
Net operating losses |  | $ | 223,800 |  |  | $ | 238,500 |
R&D credits |  |  | 62,200 |  |  |  | 47,500 |
Capitalized R&D |  |  | 34,800 |  |  |  | 47,500 |
Share-based compensation |  |  | 17,300 |  |  |  | 14,600 |
Other |  |  | 28,600 |  |  |  | 14,600 |
Total deferred tax assets |  |  | 366,700 |  |  |  | 362,700 |
Deferred tax liabilities: |  |  |  |  |  |  |  |
Convertible senior notes |  |  | (26,400 | ) |  |  | (31,300 | )
Fixed assets |  |  | (5,100 | ) |  |  | (500 | )
Total deferred tax liabilities |  |  | (31,500 | ) |  |  | (31,800 | )
Net of deferred tax assets and liabilities |  |  | 335,200 |  |  |  | 330,900 |
Valuation allowance |  |  | (335,200 | ) |  |  | (330,900 | )
Net deferred tax assets |  | $ | — |  |  | $ | — |
Activity Related to Unrecognized Tax Benefits | The following table summarizes the activity related to unrecognized tax benefits:
(in thousands) |  | 2018 |  |  | 2017 |  |  | 2016 |
Balance as of the beginning of the year |  | $ | 37,403 |  |  | $ | 34,112 |  |  | $ | 33,074 |
Increases related to prior year tax positions |  |  | 6,103 |  |  |  | — |  |  |  | 260 |
Increases related to current year tax positions |  |  | 11,726 |  |  |  | 3,291 |  |  |  | 2,211 |
Expiration of the statute of limitations for the assessment of taxes |  |  | (457 | ) |  |  | — |  |  |  | (1,433 | )
Balance as of the end of the year |  | $ | 54,775 |  |  | $ | 37,403 |  |  | $ | 34,112 |

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