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Subsequent Events - Additional Information (Detail) - USD ($) |  | 12 Months Ended
--- | --- | ---
Jan. 28, 2019 | Dec. 31, 2018
Maximum |  |
Subsequent Event [Line Items] |  |
Milestone payables |  | $ 1,000,000,000
Voyager Therapeutics | Collaboration and License Agreement |  |
Subsequent Event [Line Items] |  |
Collaborative arrangement right description |  | Under the terms of the agreement, on a program-by-program basis, upon the achievement of milestones or metrics specified in the agreement for VY-AADC and VY-FXN01, Voyager will have the option to co-develop and co-commercialize such program with the Company in the U.S. under cost- and profit-sharing arrangements, and Voyager agrees to forfeit certain milestones and royalties related to such program for which Voyager has exercised its co-develop and co-commercialize option.
Voyager Therapeutics | Subsequent Event | Collaboration and License Agreement |  |
Subsequent Event [Line Items] |  |
Up-front cash payable | $ 115,000,000 |
Collaborative agreement equity investment amount | 50,000,000 |
Voyager Therapeutics | Subsequent Event | Collaboration and License Agreement | Development, Regulatory and Commercial Milestone Payment | Maximum |  |
Subsequent Event [Line Items] |  |
Milestone payables | $ 1,700,000,000 |

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