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SHARE-BASED COMPENSATION (Tables)

12 Months Ended

Dec. 31, 2018

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Compensation Cost Related to Share Based Compensation

Share-Based Compensation. The compensation cost that has been included in the statement of comprehensive income (loss) for all share-based compensation arrangements is as follows:

	Year Ended December 31,
(in thousands)	2018				2017				2016
Sales, general and administrative expense	$	31,847			$	27,951			$	16,770
Research and development expense		26,221				14,571				11,694
Share-based compensation expense	$	58,068			$	42,522			$	28,464

Weighted-Average Assumptions for Stock Option Grants using Black-Scholes Option-Pricing Model

The estimated fair value of each stock option award granted was determined on the date of grant using the Black-Scholes option-pricing valuation model with the following weighted-average assumptions for option grants during the three years ended December 31, 2018:

	Year Ended December 31,
(in thousands)	2018				2017				2016
Risk-free interest rate		2.5	%			2.0	%			1.4	%
Expected volatility of common stock		59.5	%			58.0	%			60.0	%
Dividend yield		0.0	%			0.0	%			0.0	%
Expected option term	4.7 years				5.7 years				5.6 years

Summary and Changes in Stock Options Outstanding

A summary of the status of the Company’s stock options as of December 31, 2018, 2017 and 2016 and of changes in options outstanding under the plans during the three years ended December 31, 2018 is as follows:

	2018								2017								2016
(in thousands, except weighted average data)	Options				Weighted Average Exercise Price				Options				Weighted Average Exercise Price				Options				Weighted Average Exercise Price
Outstanding at January 1		6,356			$	28.83				6,112			$	20.01				5,507			$	15.63
Granted		1,040				84.97				1,807				46.55				1,077				40.19
Exercised		(1,592	)			18.95				(1,353	)			10.41				(341	)			7.60
Canceled		(58	)			64.67				(210	)			43.05				(131	)			34.35
Outstanding at December 31		5,746			$	41.38				6,356			$	28.83				6,112			$	20.01

Summary and Changes in Restricted Stock Units Outstanding

A summary of the status of the Company’s RSUs as of December 31, 2018, 2017, and 2016 and of changes in RSUs outstanding under the plans for the three years ended December 31, 2018 is as follows:

	2018								2017								2016
(in thousands, except weighted average data)	Number of Units				Weighted Average Grant Date Fair Value per Unit				Number of Units				Weighted Average Grant Date Fair Value per Unit				Number of Units				Weighted Average Grant Date Fair Value per Unit
Outstanding at January 1		1,080			$	40.30				883			$	29.33				910			$	24.23
Granted		540				85.29				588				47.21				326				36.73
Cancelled		(58	)			36.21				(41	)			40.62				(69	)			32.50
Converted into common shares		(429	)			59.23				(350	)			24.19				(284	)			20.71
Outstanding at December 31		1,133			$	62.31				1,080			$	40.30				883			$	29.33

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Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed.

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Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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