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Other Balance Sheet Details - Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Property, Plant and Equipment [Line Items]
Property and equipment	$ 62,140	$ 38,391
Less accumulated depreciation	(28,271)	(27,580)
Property and equipment, net	33,869	10,811
Tenant improvements
Property, Plant and Equipment [Line Items]
Property and equipment	19,857	2,019
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Property and equipment	2,968	1,303
Scientific equipment
Property, Plant and Equipment [Line Items]
Property and equipment	28,163	26,248
Computer equipment
Property, Plant and Equipment [Line Items]
Property and equipment	$ 11,152	$ 8,821

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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