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Significant Collaboration and Licensing Agreements - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands, shares in Millions | 1 Months Ended | 3 Months Ended | 9 Months Ended | 55 Months Ended | 112 Months Ended
--- | --- | --- | --- | --- | ---
Jan. 31, 2019 | Feb. 28, 2017 | Mar. 31, 2015 | Jun. 30, 2010 | Sep. 30, 2019 | Jun. 30, 2019 | Mar. 31, 2019 | Sep. 30, 2018 | Sep. 30, 2019 | Sep. 30, 2018 | Sep. 30, 2019 | Sep. 30, 2019
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Restricted investment in equity securities fair value amount |  |  |  |  | $ 48,915 |  |  |  | $ 48,915 |  | $ 48,915 | $ 48,915
Acquired in-process research and development |  |  |  |  |  |  |  |  | 118,081 |  |  |
Revenues |  |  |  |  | 222,094 |  |  | $ 151,757 | 544,077 | $ 319,748 |  |
Collaboration revenue |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  | 24,000 |  |  | $ 40,466 | 29,008 | $ 40,466 |  |
Voyager Therapeutics | Collaboration and License Agreement |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Upfront payments made | $ 115,000 |  |  |  |  |  |  |  |  |  |  |
Restricted investment in equity securities cost | $ 50,000 |  |  |  |  |  |  |  |  |  |  |
Share price | $ 11.9625 |  |  |  |  |  |  |  |  |  |  |
Restricted investment in equity securities fair value amount |  |  |  |  |  |  | $ 54,700 |  |  |  |  |
Collaboration termination notice period | 180 days |  |  |  |  |  |  |  |  |  |  |
Voyager Therapeutics | Collaboration and License Agreement | IPR&D |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Acquired in-process research and development |  |  |  |  |  | $ 5,000 | $ 113,100 |  |  |  |  |
Voyager Therapeutics | Collaboration and License Agreement | Common Stock |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Restricted investment in equity securities number of shares | 4.2 |  |  |  |  |  |  |  |  |  |  |
Voyager Therapeutics | Collaboration and License Agreement | Development, Regulatory and Commercial Milestone Payment |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Potential milestone payments | $ 1,700,000 |  |  |  |  |  |  |  |  |  |  |
B I A L |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Upfront payments made |  | $ (30,000) |  |  |  |  |  |  |  |  |  |
Potential payments for regulatory milestones |  | 40,000 |  |  |  |  |  |  |  |  |  |
Potential payments for commercial milestones |  | $ 75,000 |  |  |  |  |  |  |  |  |  |
B I A L | Regulatory and Clinical Results and FDA Acceptance Milestones |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Payments made for regulatory milestones |  |  |  |  | 10,000 |  |  |  | 10,000 |  | 10,000 | 10,000
B I A L | Development and Regulatory Milestone Payments |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Payments made for regulatory milestones |  |  |  |  | 20,000 |  |  |  | $ 20,000 |  | 20,000 | 20,000
Mitsubishi Tanabe |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Upfront payments received |  |  | $ 30,000 |  |  |  |  |  |  |  | 30,000 |
Potential milestone payment receipts |  |  | 85,000 |  |  |  |  |  |  |  |  |
Deferred revenues |  |  | 10,200 |  |  |  |  |  |  |  |  |
Mitsubishi Tanabe | Collaboration revenue |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  | $ 19,800 |  |  |  |  |  |  |  | $ 15,000 |
AbbVie |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Potential payments for commercial milestones |  |  |  | $ 50,000 |  |  |  |  |  |  |  |
Upfront payments received |  |  |  | 75,000 |  |  |  |  |  |  |  |
Potential development and regulatory milestone payment receipts |  |  |  | $ 480,000 |  |  |  |  |  |  |  |
AbbVie | Collaboration revenue |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  | $ 20,000 |  |  |  |  |  |  | $ 135,000

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