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Condensed Consolidated Statements of Income And Comprehensive Income - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Revenues:        
Revenues $ 222,094 $ 151,757 $ 544,077 $ 319,748
Operating expenses:        
Cost of sales 2,229 1,551 4,966 3,355
Research and development 45,278 35,482 144,617 121,417
Acquired in-process research and development     118,081  
Selling, general and administrative 84,489 60,401 252,851 179,952
Total operating expenses 131,996 97,434 520,515 304,724
Operating income 90,098 54,323 23,562 15,024
Other (expense) income:        
Interest expense (8,038) (7,672) (23,833) (22,767)
Unrealized loss on restricted equity securities (28,450)   (5,805)  
Investment income and other, net 4,797 4,113 13,980 10,776
Total other expense, net (31,691) (3,559) (15,658) (11,991)
Income before provision for income taxes 58,407 50,764 7,904 3,033
Provision for income taxes 4,618   4,892  
Net income 53,789 50,764 3,012 3,033
Unrealized gain (loss) on available-for-sale debt securities, net of tax 961 753 3,538 (206)
Comprehensive income $ 54,750 $ 51,517 $ 6,550 $ 2,827
Net income per share, basic $ 0.59 $ 0.56 $ 0.03 $ 0.03
Net income per share, diluted $ 0.56 $ 0.52 $ 0.03 $ 0.03
Weighted average common shares outstanding, basic 91,859 90,555 91,440 90,064
Weighted average common shares outstanding, diluted 96,074 96,798 95,231 95,272
Product sales, net        
Revenues:        
Revenues $ 198,094 $ 111,291 $ 515,069 $ 279,282
Collaboration revenue        
Revenues:        
Revenues $ 24,000 $ 40,466 $ 29,008 $ 40,466