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Components of Deferred Tax Assets (Detail) - USD ($) $ in Thousands | Dec. 31, 2019 | Dec. 31, 2018
--- | --- | ---
Deferred tax assets: |  |
Net operating losses | $ 181,300 | $ 223,800
Research and development credits | 71,900 | 62,200
Capitalized research and development | 28,000 | 34,800
Share-based compensation expense | 22,900 | 17,300
Operating lease assets | 23,300 | 100
Intangible assets | 49,300 | 9,400
Other | 18,500 | 19,100
Total deferred tax assets | 395,200 | 366,700
Deferred tax liabilities: |  |
Convertible senior notes | (24,100) | (26,400)
Operating lease liabilities | (18,200) |
Other | (6,900) | (5,100)
Total deferred tax liabilities | (49,200) | (31,500)
Net of deferred tax assets and liabilities | 346,000 | 335,200
Valuation allowance | $ (346,000) | $ (335,200)

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