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Organization and Summary of Significant Accounting Policies - Additional Information (Detail)
$ in Thousands, shares in Millions
 12 Months Ended
May 02, 2017
shares
Dec. 31, 2019
USD ($)
Site
Customer
shares
Dec. 31, 2018
USD ($)
Customer
Dec. 31, 2017
USD ($)
Customer
Jan. 01, 2019
USD ($)
Organization And Summary Of Significant Accounting Policies [Line Items]          
Other-than-temporary Impairment   $ 0 $ 0    
Transfers between levels in the fair value hierarchy   0 0    
Depreciation   7,452 $ 4,024 $ 2,400  
Right-of-use (ROU) assets   74,364      
Operating lease liabilities   $ 95,038      
ASU 2016-02          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Right-of-use (ROU) assets         $ 50,000
Operating lease liabilities         70,900
Derecognition of deferred rent for certain lease incentives received         20,900
Recognition of Deferred Gain on Sale of Real Estate | ASU 2016-02          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Deferred gain on sale of real estate as cumulative-effect adjustment to equity         $ 8,000
2.25% Convertible Senior Notes due 2024          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Shares issued to settle notes at initial conversion rate | shares 6.8        
Performance-based RSUs          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Share equivalents excluded from computation of earnings per share | shares   0.3      
ESPP          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Purchase period   6 months      
Customer Concentration Risk | Accounts Receivable          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Number of customers | Customer   2 3 3  
Customer Concentration Risk | Sales Revenue, Goods, Net          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Number of customers | Customer   2 3 3  
Percentage of product revenue   86.00% 93.00% 93.00%  
Ingrezza          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Number of separate commercial production sites | Site   2      
Advertising costs   $ 40,600 $ 20,500 $ 10,100  
Minimum          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Average estimated useful life of equipment   3 years      
Requisite service period of award   3 years      
Maximum          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Average estimated useful life of equipment   7 years      
Requisite service period of award   4 years      
In Process Research and Development          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Prior Period Reclassifications     $ 4,800 $ 30,000