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Other Balance Sheet Details - Property and Equipment (Detail) - USD ($)
$ in Thousands
Dec. 31, 2019
Dec. 31, 2018
Property, Plant and Equipment [Line Items]    
Property and equipment $ 75,473 $ 62,140
Less accumulated depreciation (33,559) (28,271)
Total property and equipment, net 41,914 33,869
Tenant improvements    
Property, Plant and Equipment [Line Items]    
Property and equipment 26,342 19,857
Furniture and fixtures    
Property, Plant and Equipment [Line Items]    
Property and equipment 3,188 2,968
Scientific equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment 33,483 28,163
Computer equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment $ 12,460 $ 11,152