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Provision for Income Taxes on Earnings Subject to Income Taxes Differs from Statutory Federal Rate (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]      
Federal income taxes at 21% for 2019 and 2018 and 35% for 2017 $ 9,775 $ 4,587 $ (49,889)
State income tax, net of federal benefit 4,044 361 (4,013)
Tax effect on non-deductible expenses 855 446 433
Branded prescription drug fee 3,707    
Share-based compensation expense (12,785) (9,778) (19,589)
Officer compensation 3,068 915 2,163
Change in tax rate (4,143) (198) 154,415
Expired tax attributes 1,228 13,874 2,998
Research credits (10,359) (13,526) (5,596)
Change in valuation allowance 13,883 4,306 (79,966)
Other 257 (257) $ (956)
Income Tax Expense (Benefit), Total $ 9,530 $ 730