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Fair Value Measurements
6 Months Ended
Jun. 30, 2020
Fair Value Disclosures [Abstract]  
Fair Value Measurements Fair Value Measurements
Investments at June 30, 2020, which were measured at fair value on a recurring basis, consisted of the following:
Fair Value Measurements Using
(in millions)Fair ValueLevel 1Level 2Level 3
Cash and cash equivalents:
Cash and money market funds$415.1  $415.1  $—  $—  
Total cash and cash equivalents415.1  415.1  —  —  
Restricted cash:
Certificates of deposit3.2  3.2  —  —  
Total restricted cash3.2  3.2  —  —  
Debt securities available-for-sale:
Commercial paper140.1  —  140.1  —  
Corporate debt securities465.0  —  465.0  —  
Securities of government-sponsored entities123.3  —  123.3  —  
Total debt securities available-for-sale728.4  —  728.4  —  
Equity securities:
Equity securities–biotechnology industry50.7  —  —  50.7  
Total equity securities50.7  —  —  50.7  
Total recurring fair value measurements$1,197.4  $418.3  $728.4  $50.7  
Investments at December 31, 2019, which were measured at fair value on a recurring basis, consisted of the following:
Fair Value Measurements Using
(in millions)Fair ValueLevel 1Level 2Level 3
Cash and cash equivalents:
Cash and money market funds$112.3  $112.3  
Total cash and cash equivalents112.3  112.3  
Restricted cash:
Certificates of deposit3.2  3.2  
Total restricted cash3.2  3.2  
Debt securities available-for-sale:
Commercial paper144.5  144.5  
Corporate debt securities521.9  521.9  
Securities of government-sponsored entities191.5  191.5  
Total debt securities available-for-sale857.9  857.9  
Equity securities:
Equity securities–biotechnology industry55.9  55.9  
Total equity securities55.9  55.9  
Total recurring fair value measurements$1,029.3  $115.5  $857.9  $55.9  
The following table presents a reconciliation of equity security investments, which were measured at fair value on a recurring basis using significant unobservable inputs (Level 3):
Three Months Ended
June 30,
Six Months Ended
June 30,
(in millions)2020201920202019
Balance at beginning of period$39.4  $56.4  $55.9  $—  
Purchases—  —  —  54.7  
Unrealized gains (losses) included in earnings11.3  21.0  (5.2) 22.7  
Balance at end of period$50.7  $77.4  $50.7  $77.4  
At June 30, 2020, the discount for lack of marketability used in the valuation analysis of equity securities ranged from 17.5% to 31.5% (weighted average of 27.5%). The discount for lack of marketability was weighted by the relative fair value of the
instruments. A significant increase (decrease) in the discount for lack of marketability in isolation would result in a significantly lower (higher) fair value measurement. Unrealized gains and losses on equity securities are included in other income (expense), net.