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Income Taxes - Provision for Income Taxes on Earnings Subject to Income Taxes Differs from Statutory Federal Rate (Details) - USD ($) $ in Millions | 12 Months Ended
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Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Income Tax Disclosure [Abstract] |  |  |
Federal income taxes, rate | 21.00% | 21.00% | 21.00%
Federal income taxes at 21% for 2020, 2019, 2018 | $ 22.4 | $ 9.8 | $ 4.6
State income tax, net of federal benefit | 5.5 | 4.0 | 0.4
Non-deductible expenses | 0.6 | 0.8 | 0.4
Branded prescription drug fee | 4.9 | 3.7 | 0.0
Share-based compensation expense | (6.7) | (12.8) | (9.8)
Officer compensation | 3.7 | 3.1 | 0.9
Change in tax rate | 3.3 | (4.1) | (0.2)
Expired tax attributes | 1.1 | 1.2 | 13.9
Research credits | (39.0) | (10.4) | (13.5)
Change in valuation allowance | (296.3) | 13.9 | 4.3
Other | (0.1) | 0.3 | (0.3)
(Benefit from) provision for income taxes | $ (300.6) | $ 9.5 | $ 0.7

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