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Consolidated Statements Income and Comprehensive Income - USD ($)
shares in Millions, $ in Millions
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Revenues:      
Revenues $ 1,045.9 $ 788.1 $ 451.2
Operating expenses:      
Cost of sales 10.1 7.4 4.9
Research and development 275.0 200.0 155.8
Acquired in-process research and development 164.5 154.3 4.8
Selling, general and administrative 433.3 354.1 248.9
Total operating expenses 882.9 715.8 414.4
Operating income 163.0 72.3 36.8
Other (expense) income:      
Interest expense (32.8) (32.0) (30.5)
Unrealized loss on restricted equity securities (17.7) (13.0) 0.0
Loss on extinguishment of convertible senior notes (18.4) 0.0 0.0
Investment income and other, net 12.6 19.2 15.5
Total other expense, net (56.3) (25.8) (15.0)
Income before (benefit from) provision for income taxes 106.7 46.5 21.8
(Benefit from) provision for income taxes (300.6) 9.5 0.7
Net income 407.3 37.0 21.1
Unrealized gain (loss) on debt securities available-for-sale 0.4 3.4 (0.1)
Comprehensive income $ 407.7 $ 40.4 $ 21.0
Net income (loss) per share, basic (in USD per share) $ 4.38 $ 0.40 $ 0.23
Net income (loss) per share, diluted (in USD per share) $ 4.16 $ 0.39 $ 0.22
Weighted average common shares outstanding, basic (in shares) 93.1 91.6 90.2
Weighted average common shares outstanding, diluted (in shares) 97.8 95.7 95.4
Product sales, net      
Revenues:      
Revenues $ 994.1 $ 752.9 $ 409.6
Collaboration revenue      
Revenues:      
Revenues $ 51.8 $ 35.2 $ 41.6