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Summary of Quarterly Results of Operations - Additional Information (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Sep. 30, 2020
Jun. 30, 2020
Dec. 31, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Acquired in-process research and development           $ 164.5 $ 154.3 $ 4.8
Idorsia | Collaborative Arrangement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Acquired in-process research and development   $ 46.0            
Takeda | Collaborative Arrangement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Acquired in-process research and development $ 118.5              
Voyager | Collaborative Arrangement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Acquired in-process research and development       $ 5.0 $ 113.1      
Xenon | Collaborative Arrangement                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                
Acquired in-process research and development     $ 36.2