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Significant Collaboration and Licensing Agreements - Additional Information (Detail) - USD ($) $ in Millions	1 Months Ended	3 Months Ended
	Mar. 31, 2015	Jun. 30, 2021	Mar. 31, 2021	Mar. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues			$ 236.6	$ 237.1
Takeda | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone payments			1,900.0
Idorsia | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone payments			1,700.0
Xenon | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone payments			1,700.0
Voyager | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone payments			1,300.0
B I A L | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone payments			75.0
Mitsubishi Tanabe | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Deferred revenue, balance			5.7
Upfront payments received	$ 30.0
Potential milestone payment receipts			70.0
Mitsubishi Tanabe | Collaborative Arrangement | Royalty | Forecast
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues		$ 15.0
Mitsubishi Tanabe | Collaborative Arrangement | License
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues			1.1	1.3
AbbVie | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestone payment receipts			366.0
AbbVie | Collaborative Arrangement | Royalty
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues			$ 4.5	$ 4.7

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