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Other Balance Sheet Details (Tables)

12 Months Ended

Dec. 31, 2021

Other Balance Sheet Details [Abstract]

Inventories

Inventory consisted of the following:

			December 31,
(in millions)			2021						2020
Raw materials			$	11.2					$	16.6
Work in process			3.6						2.4
Finished goods			15.7						9.0
Total inventory			$	30.5					$	28.0

Property and Equipment

Property and equipment, net, consisted of the following:

			December 31,
(in millions)			2021						2020
Tenant improvements			$	34.9					$	29.5
Scientific equipment			51.6						39.2
Computer equipment			18.1						13.9
Furniture and fixtures			5.9						3.7
			110.5						86.3
Less accumulated depreciation			(51.9)						(41.7)
Total property and equipment, net			$	58.6					$	44.6

Accounts Payable and Accrued Liabilities

Accounts payable and accrued liabilities consisted of the following:

			December 31,
(in millions)			2021						2020
Accrued employee related costs			$	50.6					$	38.2
Revenue-related reserves for discounts and allowances			62.7						34.6
Accrued development costs			32.4						32.9
Current branded prescription drug fee			28.6						23.6
Accounts payable and other accrued liabilities			51.5						39.4
Total accounts payable and accrued liabilities			$	225.8					$	168.7

Reconciliation of Cash, Cash Equivalents and Restricted Cash

The following table provides a reconciliation of cash and cash equivalents and restricted cash reported within the consolidated balance sheets that sum to the total of the same such amounts shown in the consolidated statements of cash flows.

			December 31,
(in millions)			2021						2020
Cash and cash equivalents			$	340.8					$	187.1
Restricted cash			3.2						3.2
Total cash, cash equivalents and restricted cash			$	344.0					$	190.3

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