XML 60 R35.htm IDEA: XBRL DOCUMENT v3.22.0.1
Fair Value Measurements - Reconciliation of Equity Securities Measured at Fair Value on Recurring Basis (Details) - USD ($)
shares in Millions, $ in Millions
 1 Months Ended 12 Months Ended
Sep. 30, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Roll Forward]        
Equity securities, beginning balance   $ 38.2    
Purchases to acquire equity securities   4.6 $ 0.0 $ 68.9
Unrealized gain (loss) included in earnings   20.9 (17.7) (13.0)
Equity securities, ending balance   63.7 38.2  
Xenon | Collaborative Arrangement        
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Roll Forward]        
Equity securities, beginning balance     14.1  
Purchases to acquire equity securities $ 4.6      
Equity securities, ending balance $ 4.6     14.1
Equity securities number of shares (in shares) 0.3      
Fair value measurements recurring | Equity securities–biotechnology industry | Level 3        
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Roll Forward]        
Equity securities, beginning balance   38.2 55.9 0.0
Purchases to acquire equity securities   4.6 0.0 68.9
Unrealized gain (loss) included in earnings   20.9 (17.7) (13.0)
Transfers out of Level 3   (52.7) 0.0 0.0
Equity securities, ending balance   $ 11.0 $ 38.2 $ 55.9