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Fair Value Measurements (Tables)
6 Months Ended
Jun. 30, 2022
Fair Value Disclosures [Abstract]  
Investments Measured at Fair Value on Recurring Basis
The following table presents a summary of investments, which were measured at fair value on a recurring basis.
June 30,
2022
December 31,
2021
Fair
Value
LevelingFair
Value
Leveling
(in millions)Level 1Level 2Level 3Level 1Level 2Level 3
Cash and cash equivalents:
Cash and money market funds$163.3 $163.3 $— $— $340.8 $340.8 $— $— 
Restricted cash:
Certificates of deposit7.8 7.8 — — 3.2 3.2 — — 
Debt securities available-for-sale:
Commercial paper77.8 — 77.8 — 204.8 — 204.8 — 
Corporate debt securities471.8 — 471.8 — 485.5 — 485.5 — 
Securities of government-sponsored entities340.6 — 340.6 — 240.9 — 240.9 — 
Equity securities:
Equity securities–biotechnology industry83.8 83.8 — — 63.7 52.7 — 11.0 
$1,145.1 $254.9 $890.2 $— $1,338.9 $396.7 $931.2 $11.0 
Reconciliation of Our Investment in Restricted Equity Securities Measured at Fair Value on Recurring Basis Using Significant Unobservable Inputs (Level 3)
The following table presents a reconciliation of equity security investments which were measured at fair value on a recurring basis using significant unobservable inputs (Level 3).
Three Months Ended
June 30,
Six Months Ended
June 30,
(in millions)2022202120222021
Balance at beginning of period$— $38.9 $11.0 $38.2 
Unrealized gain included in earnings (1)
— — 20.8 0.7 
Transfers out of Level 3 (2)
— — (31.8)— 
Balance at end of period$— $38.9 $— $38.9 
_________________________
(1) Unrealized gains and losses on restricted equity security investments were measured at fair value on a recurring basis using significant unobservable inputs (Level 3) and are included in other income (expense), net.
(2) In the first quarter of 2022, our equity security investment in Voyager was transferred from Level 3 to Level 1 as the associated holding period restriction expired.