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Income Taxes - Provision for Income Taxes on Earnings Subject to Income Taxes Differs from Statutory Federal Rate (Details) - USD ($) $ in Millions | 12 Months Ended
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Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Income Tax Disclosure [Abstract] |  |  |
Federal income taxes, rate | 21.00% | 21.00% | 21.00%
Federal income taxes at 21% | $ 44.9 | $ 21.3 | $ 22.4
State income tax, net of federal benefit | 11.8 | 6.2 | 5.5
Branded prescription drug fee | 6.5 | 4.8 | 4.9
Loss on extinguishment of convertible senior notes | 12.0 | 0.0 | 0.0
Stock-based compensation expense | (2.5) | (11.3) | (6.7)
Officer compensation | 9.2 | 7.0 | 3.7
Change in tax rate | (1.3) | 0.2 | 3.3
Expired tax attributes | 0.0 | 0.6 | 1.1
Research credits | (29.9) | (22.0) | (39.0)
Change in valuation allowance | 7.4 | 5.0 | (296.3)
Other | 1.3 | 0.0 | 0.5
Provision for (benefit from) income taxes | $ 59.4 | $ 11.8 | $ (300.6)

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