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Subsequent Events (Details) - Voyager - Collaborative Arrangement - USD ($) $ in Millions | Jan. 08, 2023 | Dec. 31, 2019
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Subsequent Event [Line Items] |  |
Upfront payments made |  | $ 165.0
Subsequent Event |  |
Subsequent Event [Line Items] |  |
Upfront payments made | $ 175.0 |
Equity investment to acquire the worldwide rights | $ 39.0 |

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- Definition Business Acquisition, Equity Investment To Acquire The Worldwide Rights + References No definition available. + Details
Name: | nbix_BusinessAcquisitionEquityInvestmentToAcquireTheWorldwideRights
Namespace Prefix: | nbix_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

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- Definition Upfront payments made under a collaboration agreement. + References No definition available. + Details
Name: | nbix_UpfrontPaymentsMade
Namespace Prefix: | nbix_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

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- Definition Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event. + References No definition available. + Details
Name: | us-gaap_SubsequentEventLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

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- Details
Name: | srt_CounterpartyNameAxis=nbix_VoyagerTherapeuticsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | us-gaap_TypeOfArrangementAxis=us-gaap_CollaborativeArrangementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |