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Consolidated Statements Income and Comprehensive Income - USD ($)
shares in Millions, $ in Millions
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Revenues:      
Revenues $ 1,488.7 $ 1,133.5 $ 1,045.9
Operating expenses:      
Cost of revenues 23.2 14.3 10.1
Research and development 463.8 328.1 275.0
Acquired in-process research and development 0.0 105.3 164.5
Selling, general and administrative 752.7 583.3 433.3
Total operating expenses 1,239.7 1,031.0 882.9
Operating income 249.0 102.5 163.0
Other (expense) income:      
Interest expense (7.1) (25.8) (32.8)
Unrealized gain (loss) on equity securities 30.8 20.9 (17.7)
Loss on extinguishment of convertible senior notes (70.0) 0.0 (18.4)
Investment income and other, net 11.2 3.8 12.6
Total other expense, net (35.1) (1.1) (56.3)
Income before provision for (benefit from) income taxes 213.9 101.4 106.7
Provision for (benefit from) income taxes 59.4 11.8 (300.6)
Net income 154.5 89.6 407.3
Foreign currency translation adjustments 2.9 0.0 0.0
Unrealized (loss) gain on debt securities available-for-sale, net of tax (9.1) (3.5) 0.4
Comprehensive income $ 148.3 $ 86.1 $ 407.7
Earnings per share, basic (in USD per share) $ 1.61 $ 0.95 $ 4.38
Earnings per share, diluted (in USD per share) $ 1.56 $ 0.92 $ 4.16
Weighted average common shares outstanding, basic (in shares) 95.8 94.6 93.1
Weighted average common shares outstanding, diluted (in shares) 98.9 97.9 97.8
Product sales, net      
Revenues:      
Revenues $ 1,440.9 $ 1,090.1 $ 994.1
Collaboration revenue      
Revenues:      
Revenues $ 47.8 $ 43.4 $ 51.8