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Condensed Consolidated Statements of Operations and Comprehensive (Loss) Income - USD ($)
shares in Millions, $ in Millions
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Revenues:    
Revenues $ 420.4 $ 310.6
Operating expenses:    
Cost of revenues 8.5 4.6
Research and development 139.5 102.2
Acquired in-process research and development 143.9 0.0
Selling, general and administrative 242.7 200.7
Total operating expenses 534.6 307.5
Operating (loss) income (114.2) 3.1
Other income (expense):    
Interest expense (1.1) (2.6)
Unrealized gain on equity security investments 2.2 19.9
Investment income and other, net 9.8 1.0
Total other income, net 10.9 18.3
(Loss) income before (benefit from) provision for income taxes (103.3) 21.4
(Benefit from) provision for income taxes (26.7) 7.5
Net (loss) income (76.6) 13.9
Foreign currency translation adjustments, net of tax 1.2 0.0
Unrealized gain (loss) on debt securities available-for-sale, net of tax 4.0 (7.6)
Comprehensive (loss) income $ (71.4) $ 6.3
(Loss) earnings per share:    
Basic (in USD per share) $ (0.79) $ 0.15
Diluted (in USD per share) $ (0.79) $ 0.14
Weighted-average shares outstanding:    
Basic (in shares) 97.1 95.3
Diluted (in shares) 97.1 97.6
Net product sales    
Revenues:    
Revenues $ 415.3 $ 305.0
Collaboration revenues    
Revenues:    
Revenues $ 5.1 $ 5.6