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The amount of the write-off for research and development assets that were acquired in a transaction other than a business combination.

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Collaboration and License Agreements (Details) $ / shares in Units, shares in Millions, $ in Millions	3 Months Ended							6 Months Ended		12 Months Ended
	Jun. 30, 2023 USD ($)	Mar. 31, 2023 USD ($) geneTherapyProgram $ / shares shares	Sep. 30, 2022 USD ($)	Jun. 30, 2022 USD ($)	Mar. 31, 2022 USD ($) $ / shares shares	Jun. 30, 2019 USD ($)	Mar. 31, 2019 USD ($) $ / shares shares	Jun. 30, 2023 USD ($)	Jun. 30, 2022 USD ($)	Dec. 31, 2021 USD ($) $ / shares shares	Dec. 31, 2020 USD ($) non-clinicalStageCompound	Dec. 31, 2019 USD ($) undisclosedProgram preclinicalCandidate $ / shares shares	Dec. 31, 2022 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Acquired in-process research and development	$ 0.0			$ 0.0				$ 143.9	$ 0.0
Unrealized gain (loss) on equity security investments	37.3			(7.4)				39.5	12.5
Equity security investments	173.0							173.0					$ 102.1
Revenues	452.7			378.2				873.1	688.8
Collaborative Arrangement \| Common Stock \| 2023 Voyager Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Beneficial ownership percentage		19.90%
Heptares \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Acquired in-process research and development										$ 100.0
Research and development				30.0
Potential milestone payments	2,600.0							2,600.0
Agreement termination, minimal contractual time										180 days
Agreement termination, contractual time threshold										90 days
Agreement termination by counterparty, contractual time threshold										365 days
Agreement termination by counterparty, minimal contractual time										120 days
Takeda \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Acquired in-process research and development											$ 120.0
Research and development			$ 5.0
Potential milestone payments	1,900.0							1,900.0
Agreement termination, minimal contractual time											6 months
Agreement termination, contractual time threshold											12 months
Number of non-clinical stage compounds \| non-clinicalStageCompound											4
Idorsia \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Acquired in-process research and development											$ 45.0
Potential milestone payments	1,700.0							1,700.0
Agreement termination, minimal contractual time											90 days
Agreement termination, due to material breach											90 days
Xenon \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Acquired in-process research and development												$ 36.2
Research and development					$ 7.3					$ 5.4
Potential milestone payments	1,700.0							1,700.0
Agreement termination, contractual time threshold												90 days
Number of preclinical candidates \| preclinicalCandidate												3
Upfront payment												$ 50.0
Share price (in USD per share) \| $ / shares					$ 31.855					$ 19.9755		$ 14.196
Equity securities fair value (Level 3)										$ 4.6		$ 14.1
Milestone payment					$ 15.0					$ 10.0
Equity securities fair value (Level 1)					$ 7.7
Xenon \| Collaborative Arrangement \| Common Stock
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sale of stock (in shares) \| shares					0.3					0.3		1.4
Voyager \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Number of undisclosed programs \| undisclosedProgram												2
Unrealized gain (loss) on equity security investments	32.1							41.3
Equity security investments	98.2							98.2
2019 Voyager Agreement \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Acquired in-process research and development						$ 5.0	$ 113.1
Potential milestone payments	1,300.0							$ 1,300.0
Agreement termination, minimal contractual time							180 days
Agreement termination, contractual time threshold							1 year
Upfront payment							$ 165.0
Share price (in USD per share) \| $ / shares							$ 11.9625
Equity securities fair value (Level 3)							$ 54.7
Voting restriction period		3 years
2019 Voyager Agreement \| Collaborative Arrangement \| Common Stock
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sale of stock (in shares) \| shares							4.2
2023 Voyager Agreement \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Acquired in-process research and development		$ 143.9
Potential milestone payments		$ 6,100.0
Agreement termination, minimal contractual time		180 days
Agreement termination, contractual time threshold		1 year
Upfront payment		$ 175.0
Share price (in USD per share) \| $ / shares		$ 8.88
Equity securities fair value (Level 1)		$ 31.3
Voting restriction period		3 years
Number of gene therapy programs \| geneTherapyProgram		3
Board of directors maximum duration term		10 years
2023 Voyager Agreement \| Collaborative Arrangement \| Common Stock
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sale of stock (in shares) \| shares		4.4
MTPC \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Agreement termination, contractual time threshold								180 days
Revenues				20.0
Potential milestone payment receipts	30.0							$ 30.0
MTPC \| Collaborative Arrangement \| Minimum \| Patents
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Patent term								10 years
AbbVie \| Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Agreement termination, contractual time threshold								180 days
Potential milestone payment receipts	366.0							$ 366.0
AbbVie \| Collaborative Arrangement \| Royalty
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues	$ 4.2			$ 5.2				$ 7.9	$ 9.4
AbbVie \| Collaborative Arrangement \| Minimum \| Patents
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Patent term								10 years