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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) (unaudited) - USD ($)
shares in Millions, $ in Millions
 3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Revenues:    
Total revenues $ 515.3 $ 420.4
Operating expenses:    
Cost of revenues 7.5 8.5
Research and development 159.4 139.5
Acquired in-process research and development 6.0 143.9
Selling, general and administrative 243.1 242.7
Total operating expenses 416.0 534.6
Operating income (loss) 99.3 (114.2)
Other (expense) income:    
Interest expense (1.1) (1.1)
Unrealized gain on equity security investments 1.6 2.2
Charges associated with convertible senior notes (88.7) 0.0
Investment income and other, net 23.4 9.8
Total other (expense) income, net (64.8) 10.9
Income (loss) before benefit from income taxes 34.5 (103.3)
Benefit from income taxes (8.9) (26.7)
Net income (loss) 43.4 (76.6)
Foreign currency translation adjustments, net of tax (0.5) 1.2
Unrealized (loss) gain on debt securities available-for-sale, net of tax (3.2) 4.0
Comprehensive income (loss) $ 39.7 $ (71.4)
Earnings (loss) per share:    
Basic (in USD per share) $ 0.43 $ (0.79)
Diluted (in USD per share) $ 0.42 $ (0.79)
Weighted-average shares outstanding:    
Basic (in shares) 99.8 97.1
Diluted (in shares) 103.6 97.1
Net product sales    
Revenues:    
Total revenues $ 509.0 $ 415.3
Collaboration revenues    
Revenues:    
Total revenues $ 6.3 $ 5.1