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Income Taxes - Provision for Income Taxes on Earnings Subject to Income Taxes Differs from Statutory Federal Rate (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Income Tax Disclosure [Abstract]
Federal income taxes, rate	21.00%	21.00%	21.00%
Federal income taxes at 21%	$ 102.1	$ 69.7	$ 44.9
State income tax, net of federal benefit	34.6	17.5	11.8
Branded prescription drug fee	7.5	8.7	6.5
Loss on extinguishment of convertible senior notes	29.1	0.0	12.0
Stock-based compensation expense	(20.4)	(3.9)	(2.5)
Officer compensation	3.3	9.6	9.2
Foreign rate differential	7.2	3.4	(0.2)
Change in tax rate	(0.6)	(5.5)	(1.1)
Research credits	(49.2)	(42.2)	(29.9)
Change in valuation allowance	23.9	22.0	7.4
Other	7.2	3.1	1.3
Provision for income taxes	$ 144.7	$ 82.4	$ 59.4

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