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CONDENSED CONSOLIDATED STATEMENTS OF INCOME AND COMPREHENSIVE INCOME (unaudited) - USD ($)
shares in Millions, $ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Revenues:        
Total revenues $ 687.5 $ 590.2 $ 1,260.1 $ 1,105.5
Operating expenses:        
Cost of revenues 11.3 9.2 20.5 16.7
Research and development 244.3 191.1 507.5 350.5
Acquired in-process research and development 0.0 2.5 0.1 8.5
Selling, general, and administrative 286.3 242.0 562.8 485.1
Total operating expenses 541.9 444.8 1,090.9 860.8
Operating income 145.6 145.4 169.2 244.7
Other income (expense):        
Unrealized loss on equity investments (6.7) (19.9) (37.3) (18.3)
Charges associated with convertible senior notes 0.0 (49.7) 0.0 (138.4)
Investment income and other, net 20.6 22.8 42.3 45.1
Total other income (expense), net 13.9 (46.8) 5.0 (111.6)
Income before provision for income taxes 159.5 98.6 174.2 133.1
Provision for income taxes 52.0 33.6 58.8 24.7
Net income 107.5 65.0 115.4 108.4
Foreign currency translation adjustments, net of tax 0.8 0.1 2.3 (0.4)
Unrealized gain (loss) on available-for-sale debt securities, net of tax 2.7 (0.9) 4.4 (4.1)
Comprehensive income $ 111.0 $ 64.2 $ 122.1 $ 103.9
Earnings per share:        
Basic (in USD per share) $ 1.09 $ 0.64 $ 1.16 $ 1.08
Diluted (in USD per share) $ 1.06 $ 0.63 $ 1.13 $ 1.04
Weighted-average shares outstanding:        
Basic (in shares) 99.0 100.8 99.3 100.3
Diluted (in shares) 101.0 103.9 101.8 103.8
Net product sales        
Revenues:        
Total revenues $ 682.0 $ 583.8 $ 1,245.7 $ 1,092.8
Collaboration revenues        
Revenues:        
Total revenues $ 5.5 $ 6.4 $ 14.4 $ 12.7