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v3.25.3

Segment Reporting and Disaggregation of Relevant Expense Captions - Segment Reporting Information, by Segment (Details) - USD ($) $ in Millions | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Segment Reporting Information [Line Items] |  |  |  |
Total revenues | $ 794.9 | $ 622.1 | $ 2,055.0 | $ 1,727.6
Less: |  |  |  |
Cost of revenues | 14.0 | 8.0 | 34.5 | 24.7
Total research and development | 250.0 | 195.0 | 757.5 | 545.5
Acquired in-process research and development | 0.3 | 1.0 | 0.4 | 9.5
Selling, general, and administrative | 291.6 | 234.3 | 854.4 | 719.4
Unrealized (gain) loss on equity investments | (30.6) | 16.9 | 6.7 | 35.2
Charges associated with convertible senior notes | 0.0 | 0.0 | 0.0 | 138.4
Interest income and other, net | (22.2) | (23.4) | (64.5) | (68.5)
Provision for income taxes | 82.3 | 60.5 | 141.1 | 85.2
Net income | 209.5 | 129.8 | 324.9 | 238.2
Reportable Segment |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Total revenues | 794.9 | 622.1 | 2,055.0 | 1,727.6
Less: |  |  |  |
Cost of revenues | 14.0 | 8.0 | 34.5 | 24.7
Total research and development | 250.0 | 195.0 | 757.5 | 545.5
Acquired in-process research and development | 0.3 | 1.0 | 0.4 | 9.5
Selling, general, and administrative | 291.6 | 234.3 | 854.4 | 719.4
Unrealized (gain) loss on equity investments | (30.6) | 16.9 | 6.7 | 35.2
Charges associated with convertible senior notes | 0.0 | 0.0 | 0.0 | 138.4
Interest income and other, net | (22.2) | (23.4) | (64.5) | (68.5)
Provision for income taxes | 82.3 | 60.5 | 141.1 | 85.2
Net income | 209.5 | 129.8 | 324.9 | 238.2
Reportable Segment | INGREZZA net product sales |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Total revenues | 686.6 | 612.9 | 1,856.2 | 1,698.4
Reportable Segment | CRENESSITY net product sales |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Total revenues | 98.1 | 0.0 | 165.8 | 0.0
Reportable Segment | Other revenues |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Total revenues | 10.2 | 9.2 | 33.0 | 29.2
Reportable Segment | External research and development |  |  |  |
Less: |  |  |  |
Total research and development | 141.8 | 82.9 | 370.3 | 250.4
Reportable Segment | Payroll and benefits |  |  |  |
Less: |  |  |  |
Total research and development | 74.6 | 55.4 | 221.8 | 167.9
Reportable Segment | Milestones |  |  |  |
Less: |  |  |  |
Total research and development | 1.0 | 38.8 | 61.5 | 71.4
Reportable Segment | Other research and development |  |  |  |
Less: |  |  |  |
Total research and development | $ 32.6 | $ 17.9 | $ 103.9 | $ 55.8

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