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CONDENSED CONSOLIDATED STATEMENTS OF INCOME AND COMPREHENSIVE INCOME (unaudited) - USD ($) shares in Millions, $ in Millions | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Revenues: |  |  |  |
Total revenues | $ 794.9 | $ 622.1 | $ 2,055.0 | $ 1,727.6
Operating expenses: |  |  |  |
Cost of revenues | 14.0 | 8.0 | 34.5 | 24.7
Research and development | 250.0 | 195.0 | 757.5 | 545.5
Acquired in-process research and development | 0.3 | 1.0 | 0.4 | 9.5
Selling, general, and administrative | 291.6 | 234.3 | 854.4 | 719.4
Total operating expenses | 555.9 | 438.3 | 1,646.8 | 1,299.1
Operating income | 239.0 | 183.8 | 408.2 | 428.5
Other income (expense): |  |  |  |
Unrealized gain (loss) on equity investments | 30.6 | (16.9) | (6.7) | (35.2)
Charges associated with convertible senior notes | 0.0 | 0.0 | 0.0 | (138.4)
Investment income and other, net | 22.2 | 23.4 | 64.5 | 68.5
Total other income (expense), net | 52.8 | 6.5 | 57.8 | (105.1)
Income before provision for income taxes | 291.8 | 190.3 | 466.0 | 323.4
Provision for income taxes | 82.3 | 60.5 | 141.1 | 85.2
Net income | 209.5 | 129.8 | 324.9 | 238.2
Foreign currency translation adjustments, net of tax | 1.6 | 2.9 | 3.9 | 2.5
Unrealized (loss) gain on available-for-sale debt securities, net of tax | (0.9) | 9.1 | 3.5 | 5.0
Comprehensive income | $ 210.2 | $ 141.8 | $ 332.3 | $ 245.7
Earnings per share: |  |  |  |
Basic (in USD per share) | $ 2.11 | $ 1.28 | $ 3.27 | $ 2.37
Diluted (in USD per share) | $ 2.04 | $ 1.24 | $ 3.19 | $ 2.29
Weighted-average shares outstanding: |  |  |  |
Basic (in shares) | 99.4 | 101.1 | 99.3 | 100.6
Diluted (in shares) | 102.5 | 104.3 | 102.0 | 104.0
Net product sales |  |  |  |
Revenues: |  |  |  |
Total revenues | $ 789.9 | $ 616.6 | $ 2,035.6 | $ 1,709.4
Collaboration revenues |  |  |  |
Revenues: |  |  |  |
Total revenues | $ 5.0 | $ 5.5 | $ 19.4 | $ 18.2

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