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CONDENSED CONSOLIDATED STATEMENTS OF INCOME AND COMPREHENSIVE INCOME (unaudited) - USD ($)
shares in Millions, $ in Millions
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Revenues:        
Total revenues $ 794.9 $ 622.1 $ 2,055.0 $ 1,727.6
Operating expenses:        
Cost of revenues 14.0 8.0 34.5 24.7
Research and development 250.0 195.0 757.5 545.5
Acquired in-process research and development 0.3 1.0 0.4 9.5
Selling, general, and administrative 291.6 234.3 854.4 719.4
Total operating expenses 555.9 438.3 1,646.8 1,299.1
Operating income 239.0 183.8 408.2 428.5
Other income (expense):        
Unrealized gain (loss) on equity investments 30.6 (16.9) (6.7) (35.2)
Charges associated with convertible senior notes 0.0 0.0 0.0 (138.4)
Investment income and other, net 22.2 23.4 64.5 68.5
Total other income (expense), net 52.8 6.5 57.8 (105.1)
Income before provision for income taxes 291.8 190.3 466.0 323.4
Provision for income taxes 82.3 60.5 141.1 85.2
Net income 209.5 129.8 324.9 238.2
Foreign currency translation adjustments, net of tax 1.6 2.9 3.9 2.5
Unrealized (loss) gain on available-for-sale debt securities, net of tax (0.9) 9.1 3.5 5.0
Comprehensive income $ 210.2 $ 141.8 $ 332.3 $ 245.7
Earnings per share:        
Basic (in USD per share) $ 2.11 $ 1.28 $ 3.27 $ 2.37
Diluted (in USD per share) $ 2.04 $ 1.24 $ 3.19 $ 2.29
Weighted-average shares outstanding:        
Basic (in shares) 99.4 101.1 99.3 100.6
Diluted (in shares) 102.5 104.3 102.0 104.0
Net product sales        
Revenues:        
Total revenues $ 789.9 $ 616.6 $ 2,035.6 $ 1,709.4
Collaboration revenues        
Revenues:        
Total revenues $ 5.0 $ 5.5 $ 19.4 $ 18.2