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Business combinations - Schedule of Proforma effect of PRA Health Sciences Inc Acquisition (Details) - PRA Health Sciences Inc - USD ($)
$ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2021
Dec. 31, 2020
Business Acquisition [Line Items]    
Revenue $ 5,580,879 $ 5,964,653
Net income/(loss) $ 231,442 $ (151,209)