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Significant accounting policies (Tables)
12 Months Ended
Dec. 31, 2021
Accounting Policies [Abstract]  
Adjustments Resulting From Foreign Currency Translations Amounts charged or credited to the Consolidated Statements of Operations for the years ended December 31, 2021, December 31, 2020 and December 31, 2019 were as follows:
Year ended
December 31,
 202120202019
(in thousands)
 
Amounts (credited)/charged
$(14,316)$5,979 $590 
Estimated Useful Lives of Assets Depreciation of property, plant and equipment is computed using the straight line method based on the estimated useful lives of the assets as listed below: 
 Years
Building  40
Computer equipment and software
2-8
Office furniture and fixtures8
Laboratory equipment  5
Motor vehicles5