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Business Segment and Geographical Information (Tables)
 12 Months Ended
Dec. 31, 2021
Segment Reporting [Abstract]  
Schedule of Distribution of Net Revenue by Geographical Area The distribution of revenue by geographical area was as follows:
 Year ended
December 31, 2021December 31, 2020December 31, 2019
 (in thousands)
Ireland$1,365,909 $1,181,292 $1,252,834 
Rest of Europe1,175,515 416,884 388,916 
U.S.2,581,007 925,563 892,497 
Other358,395 273,549 271,592 
 
Total
$5,480,826 $2,797,288 $2,805,839 
Schedule of Distribution of Income from Operations by Geographical Area
b) The distribution of income from operations, excluding restructuring, transaction and integration related expenses, by geographical area was as follows:

 Year ended
December 31, 2021December 31, 2020December 31, 2019
 (in thousands)
Ireland *$161,862 $295,360 $314,287 
Rest of Europe183,436 35,402 37,997 
U.S.231,971 56,921 60,272 
Other30,628 21,147 20,850 
 
Total
$607,897 $408,830 $433,406 
* Includes the full amount of the amortization charge associated with the intangible asset acquired in the Merger. These assets have been provisionally allocated to Ireland.
Schedule of Distribution of Long-lived Assets, Net, by Geographical Area The distribution of long-lived assets (property, plant and equipment and operating right-of-use assets), net, by geographical area was as follows:
December 31, 2021December 31, 2020
 (in thousands)
Ireland$118,253 $118,361 
Rest of Europe121,174 36,723 
U.S.239,828 65,152 
Other55,312 38,668 
 
Total
$534,567 $258,904