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Business combinations - Schedule of Proforma Information of PRA Health Sciences Inc Acquisition (Details) - PRA Health Sciences, Inc - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Business Acquisition [Line Items]    
Revenue $ 1,901,764 $ 1,791,973
Net income (loss) $ 111,970 $ (204,650)