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Business combinations - Narrative (Details)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended
Jul. 01, 2021
Employee
$ / shares
shares
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Business Acquisition [Line Items]          
Entity number of employees | Employee 38,000        
Acquisition-related costs   $ 8,001 $ 149,791 $ 28,970 $ 182,309
PRA Health Sciences, Inc          
Business Acquisition [Line Items]          
Business acquisition, share price (in USD per share) | $ / shares $ 80        
Business acquisition, number of shares issued (in shares) | shares 0.4125        
Integration-related costs       $ 29,000