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Business combinations - Schedule of Fair Value of PRA Health Sciences Inc Acquisition Consideration (Details) - USD ($)
$ in Thousands
9 Months Ended
Jul. 01, 2021
Sep. 30, 2022
Sep. 30, 2021
Business Acquisition [Line Items]      
Fair value of cash consideration   $ 0 $ 5,914,475
PRA Health Sciences, Inc      
Business Acquisition [Line Items]      
Fair value of cash consideration $ 5,308,646    
Fair value of ordinary shares issued to acquiree stockholders 5,658,126    
Fair value of replacement share-based awards issued to acquiree employees 209,399    
Repayment of term loan obligations and accrued interest 865,800    
Total consideration transferred 12,041,971    
Payments to settle debt obligations that existed prior to acquisition date $ 401,600