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Property, Plant and Equipment, net (Tables) | 12 Months Ended
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Dec. 31, 2022
Property, Plant and Equipment [Abstract] |
Schedule of Property Plant and Equipment, Net | The carrying amount of Property, Plant and Equipment for the years ended December 31, 2022 and 2021 is as follows:
| December 31, 2022 | December 31, 2021
| (in thousands)
Cost |  |
Land | $ | 3,724 |  | $ | 3,724 |
Building | 70,880 |  | 82,017 |
Computer equipment and software | 500,135 |  | 506,322 |
Office furniture and fixtures | 50,600 |  | 107,507 |
Laboratory equipment | 59,946 |  | 29,210 |
Leasehold improvements | 65,167 |  | 70,123 |
Motor vehicles | 41 |  | 65 |
| 750,493 |  | 798,968 |
Less accumulated depreciation and asset write offs | (400,173) |  | (462,524) |
Property, plant and equipment (net) | $ | 350,320 |  | $ | 336,444 |
Property, Plant and Equipment depreciation expense is as follows:
| December 31, 2022 | December 31, 2021
| (in thousands)
Depreciation expense | $ | 106,426 |  | $ | 75,484 |

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- Definition Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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