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Summary of Significant accounting policies (Tables)
 12 Months Ended
Dec. 31, 2022
Accounting Policies [Abstract]  
Adjustments resulting from foreign currency translations Amounts charged or credited to the Consolidated Statements of Operations for the years ended December 31, 2022, December 31, 2021 and December 31, 2020 were as follows:
Year ended
December 31,
 202220212020
(in thousands)
 
Amounts (credited)/charged
$(25,997)$(14,316)$5,979 
Estimated useful lives of assets Depreciation of property, plant and equipment is computed using the straight line method based on the estimated useful lives of the assets as listed below: 
 Years
Building  40
Computer equipment and software
2-8
Office furniture and fixtures8
Laboratory equipment  5
Motor vehicles5
Schedule of Finite-Lived Intangible Assets
Intangible assets are amortized on a straight-line basis over the expected useful life, as set forth in the table below:

Estimated Useful Life
Customer relationships23 years
Order backlog3 years
Trade names3 years
Patient database7 years
Technology assets5 years
The carrying amount of Intangible Assets for the years ended December 31, 2022 and 2021 is as follows:
December 31, 2022December 31, 2021
Cost(in thousands)
Customer relationships$4,076,435 $4,056,642 
Order backlog536,934 528,022 
Trade names & brands204,621 204,685 
Patient database170,238 170,525 
Technology assets120,984 121,507 
Total cost5,109,212 5,081,381 
Accumulated amortization(830,553)(370,538)
 
Net book value
$4,278,659 $4,710,843