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Property, Plant and Equipment, net
 12 Months Ended
Dec. 31, 2023
Property, Plant and Equipment [Abstract]  
Property, Plant and Equipment, net Property, Plant and Equipment, net
The carrying amount of Property, Plant and Equipment for the years ended December 31, 2023 and 2022 is as follows:
December 31, 2023December 31, 2022
 (in thousands)
Cost  
Land$3,724 $3,724 
Buildings70,072 70,880 
Computer equipment and software550,119 500,135 
Office furniture and fixtures45,856 50,600 
Laboratory equipment56,217 59,946 
Leasehold improvements55,000 65,167 
Motor vehicles79 41 
 781,067 750,493 
Less accumulated depreciation and asset write offs(419,883)(400,173)
Property, plant and equipment (net)$361,184 $350,320 

The depreciation expense recognized by the Company was $126.1 million, $106.4 million, and $75.5 million for the twelve months ended December 31, 2023, 2022, and 2021, respectively.

The Company regularly updates its register of property, plant and equipment and during the year ended December 31, 2023 and the year ended December 31, 2022, certain fully depreciated assets were written off as they were no longer used by the Company.