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Property, Plant and Equipment, net (Details) - USD ($) $ in Thousands	Dec. 31, 2023	Dec. 31, 2022
Property, Plant and Equipment [Abstract]
Land	$ 3,724	$ 3,724
Buildings	70,072	70,880
Computer equipment and software	550,119	500,135
Office furniture and fixtures	45,856	50,600
Laboratory equipment	56,217	59,946
Leasehold improvements	55,000	65,167
Motor vehicles	79	41
Property, plant and equipment, gross	781,067	750,493
Less accumulated depreciation and asset write offs	(419,883)	(400,173)
Property, plant and equipment (net)	$ 361,184	$ 350,320

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Vehicles, Gross

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Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation of building structures held for productive use including addition, improvement, or renovation to the structure, including, but not limited to, interior masonry, interior flooring, electrical, and plumbing.

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Amount before accumulated amortization of capitalized costs for computer software, including but not limited to, acquired and internally developed computer software.

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Amount before accumulated depreciation of equipment commonly used in offices and stores that have no permanent connection to the structure of a building or utilities. Examples include, but are not limited to, desks, chairs, tables, and bookcases.

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Amount before accumulated depletion of real estate held for productive use, excluding land held for sale.

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