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Equity Incentive Schemes and Stock Compensation Charges - Narrative (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended 24 Months Ended 252 Months Ended
Oct. 25, 2024
Feb. 14, 2017
May 11, 2015
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2020
Dec. 31, 2017
May 18, 2020
May 16, 2019
May 31, 2018
Feb. 13, 2017
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Weighted average contractual term of options outstanding       3 years 10 months 28 days 4 years 5 months 1 day              
Exercisable - weighted average remaining contractual life       3 years 21 days 3 years 10 months 20 days              
Options outstanding, intrinsic value (in USD)       $ 34,000                
Options exercisable, intrinsic value (in USD)       32,400                
Options exercised during period, intrinsic value (in USD)       57,400 $ 80,400 $ 41,900            
Total       45,870 55,667 70,523            
Unrecognized share-based compensation cost       $ 108,100                
Unrecognized share-based compensation cost, period of recognition       2 years 3 months 14 days                
Income tax benefit related to stock compensation       $ 23,400 20,000 12,900            
Cash tax benefit related to stock options exercised       10,100 10,900 $ 7,700            
The 2020 Legacy PRA Plan                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Ordinary shares which have been reserved for issuance (in shares)                 2,500,000      
The 2018 Legacy PRA Plan                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Ordinary shares which have been reserved for issuance (in shares)                     2,000,000  
Consultants Stock Plan, 2008 Plan                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Ordinary shares which have been reserved for issuance (in shares)   400,000                   1,000,000.0
Limit of shares issued or to be issued pursuant to options granted (in shares)   1,000,000.0                    
Employee Stock Plan, 2008 Plan                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Ordinary shares which have been reserved for issuance (in shares)   6,000,000.0                    
Maximum number of shares per employee (in shares)   400,000                    
Option Plans 2008 | Minimum                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Percentage of option price for fair value of ordinary share (in percent)   100.00%                    
Employee Stock Option | Award date, prior to 2018                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Shares expiration period               8 years        
Employee Stock Option | Award date, prior to 2018 | Minimum                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Shares vesting period               4 years        
Employee Stock Option | Award date, prior to 2018 | Maximum                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Shares vesting period               5 years        
Restricted Stock Units 2013                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Ordinary shares which have been reserved for issuance (in shares) 6,600,000                      
Additional number of ordinary shares which have been reserved for issuance (in shares) 2,500,000   2,500,000                  
Consultants Restricted Stock Units 2019                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Ordinary shares which have been reserved for issuance (in shares)                   250,000    
Consultants Restricted Stock Units 2019 | Non-executive director                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Shares vesting period             12 months          
Restricted Stock Units (RSUs)                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Fair value of stock units vested       $ 26,900 $ 35,400              
Restricted Stock Units (RSUs) | Minimum                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Share price of equity instruments other than options, vested in period (in USD per share)       $ 174.96 $ 159.33              
Restricted Stock Units (RSUs) | Maximum                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Share price of equity instruments other than options, vested in period (in USD per share)       $ 265.96 $ 265.96              
Performance Share Unit (PSUs)                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Fair value of stock units vested       $ 1,800 $ 7,500              
Performance Share Unit (PSUs) | Minimum                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Share price of equity instruments other than options, vested in period (in USD per share)       $ 174.96 $ 159.33              
Performance Share Unit (PSUs) | Maximum                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Share price of equity instruments other than options, vested in period (in USD per share)       $ 231.08 $ 166.51              
PSUs Based on Service and EPS Targets | Maximum                        
Compensation Related Costs Share Based Payments Disclosure [Line Items]                        
Stock units to be granted (in shares)       80,051