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Property, Plant and Equipment, net
 12 Months Ended
Dec. 31, 2024
Property, Plant and Equipment [Abstract]  
Property, Plant and Equipment, net Property, Plant and Equipment, net
The carrying amount of Property, Plant and Equipment for the years ended December 31, 2024 and 2023 is as follows:

December 31, 2024December 31, 2023
Cost(in thousands)
Land$3,724 $3,724 
Buildings66,132 70,072 
Computer equipment and software689,979 550,119 
Office furniture and fixtures51,849 45,856 
Laboratory equipment55,111 56,217 
Leasehold improvements62,034 55,000 
Motor vehicles65 79 
Total Cost928,894 781,067 
Less accumulated depreciation and asset write offs(546,015)(419,883)
Property, plant and equipment (net)$382,879 $361,184 

The depreciation expense recognized by the Company was $138.2 million, $126.1 million, and $106.4 million for the years ended December 31, 2024, 2023, and 2022, respectively.

The Company regularly updates its register of property, plant and equipment and during the year ended December 31, 2024 and the year ended December 31, 2023, certain fully depreciated assets were written off as they were no longer used by the Company.