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  <xs:element id="clh_NumeratorForBasicAndDilutedEarningsPerShareAbstract" abstract="true" name="NumeratorForBasicAndDilutedEarningsPerShareAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="clh_A2028TermLoansVariableRateMember" abstract="true" name="A2028TermLoansVariableRateMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="clh_IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet" abstract="false" name="IncomeLossFromContinuingOperationsBeforeInterestTaxDepreciationAndAmortizationNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="clh_ContingencyNatureDomain" abstract="true" name="ContingencyNatureDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_PermitsMember" abstract="true" name="PermitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_NumberOfSitesPotentialLiabilityExceedsSubstantialQuota" abstract="false" name="NumberOfSitesPotentialLiabilityExceedsSubstantialQuota" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAccruedAndOtherCurrentLiabilities" abstract="false" name="BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAccruedAndOtherCurrentLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="clh_BuildingsAndImprovemensMember" abstract="true" name="BuildingsAndImprovemensMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_SolventAndSolutionsMember" abstract="true" name="SolventAndSolutionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent" abstract="false" name="AccruedCappingClosurePostClosureAndRemedialLiabilitiesCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="clh_SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty" abstract="false" name="SiteContingencyNotRequiringEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="clh_SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty" abstract="false" name="SiteContingencyEnvironmentalRemediationExpenseNumberOfSitesOwnedByThirdParty" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="clh_SafetlyKleenEnvironmentalServicesMember" abstract="true" name="SafetlyKleenEnvironmentalServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour" abstract="false" name="FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="clh_DeferredContractCostRecognitionPeriod" abstract="false" name="DeferredContractCostRecognitionPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="clh_ScheduleOfFiniteLivedAndIndefiniteLivedIntangibleAssetsLineItems" abstract="true" name="ScheduleOfFiniteLivedAndIndefiniteLivedIntangibleAssetsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="clh_DebtInstrumentPrepaymentPremiumPercentage" abstract="false" name="DebtInstrumentPrepaymentPremiumPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="clh_AccretionOfEnvironmentalLiabilities" abstract="false" name="AccretionOfEnvironmentalLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="clh_DenominatorForBasicAndDilutedEarningsPerShareAbstract" abstract="true" name="DenominatorForBasicAndDilutedEarningsPerShareAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="clh_RemedialLiabilitiesForLandfillSitesMember" abstract="true" name="RemedialLiabilitiesForLandfillSitesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_SafetyKleenSustainabilitySolutionsSegmentMember" abstract="true" name="SafetyKleenSustainabilitySolutionsSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_DebtInstrumentInterestMargin" abstract="false" name="DebtInstrumentInterestMargin" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="clh_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAccountsReceivable" abstract="false" name="BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentAccountsReceivable" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="clh_SafetyKleenOilMember" abstract="true" name="SafetyKleenOilMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_ExistingTermLoansMember" abstract="true" name="ExistingTermLoansMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="clh_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedAndOtherCurrentLiabilities" abstract="false" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedAndOtherCurrentLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="clh_AccrualForEnvironmentalLossContingenciesIncreaseDecreaseForCurrencyTranslationAndOther" abstract="false" name="AccrualForEnvironmentalLossContingenciesIncreaseDecreaseForCurrencyTranslationAndOther" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="clh_A2022SwapsMember" abstract="true" name="A2022SwapsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="clh_A2024IncrementalTermLoansMember" abstract="true" name="A2024IncrementalTermLoansMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
