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Goodwill and Intangible Assets
3 Months Ended
Mar. 31, 2023
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and Intangible Assets Goodwill and Intangible Assets
Goodwill
The changes in the carrying amount of goodwill for the three months ended March 31, 2023 are as follows:
(In millions)Developed Markets (1)Greater ChinaJANZEmerging Markets (2)Total
Balance at December 31, 2022:7,461.5 940.6 689.0 1,334.7 10,425.8 
Acquisitions95.3 — — — 95.3 
Foreign currency translation60.0 — (8.6)0.7 52.1 
Balance at March 31, 2023:$7,616.8 $940.6 $680.4 $1,335.4 $10,573.2 
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(1)Balances as of March 31, 2023 and December 31, 2022 include an accumulated impairment loss of $385.0 million.
(2)Balances as of March 31, 2023 and December 31, 2022 include an accumulated impairment loss of $117.0 million.
Intangible Assets, Net
Intangible assets consist of the following components at March 31, 2023 and December 31, 2022:
(In millions)Weighted Average Life (Years)Original CostAccumulated AmortizationNet Book Value
March 31, 2023
Product rights, licenses and other (1)
15$37,975.1 $15,604.6 $22,370.5 
In-process research and development331.1 — 331.1 
$38,306.2 $15,604.6 $22,701.6 
December 31, 2022
Product rights, licenses and other (1)
15$37,490.5 $14,923.6 $22,566.9 
In-process research and development40.2 — 40.2 
$37,530.7 $14,923.6 $22,607.1 
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(1)Represents amortizable intangible assets. Other intangible assets consists principally of customer lists and contractual rights.
During the three months ended March 31, 2023, the Company acquired product rights and licenses from Oyster Point of approximately $334.0 million and IPR&D of approximately $290.0 million from Famy Life Sciences. Refer to Note 4 Acquisitions and Other Transactions for additional information.

Amortization expense and intangible asset disposal & impairment charges (which are included as a component of amortization expense) are classified primarily within cost of sales in the condensed consolidated statements of operations and were as follows for the three months ended March 31, 2023 and 2022:
Three Months Ended
March 31,
(In millions)20232022
Intangible asset amortization expense$603.3 $648.1 
Intangible asset disposal & impairment charges32.0 — 
Total intangible asset amortization expense (including disposal & impairment charges)$635.3 $648.1 
During the three months ended March 31, 2023, the Company recognized an intangible asset charge of approximately $32.0 million, which was recorded within Cost of sales in the condensed consolidated statement of operations, to write down the disposal group to fair value, less cost to sell, related to our Upjohn Distributor Markets, which are classified as held for sale. As of March 31, 2023 and December 31, 2022, the Company has approximately $198.3 million and $230.3 million, respectively, of intangible assets related to the Upjohn Distributor Markets that are classified as held for sale in the condensed consolidated balance sheets. Refer to Note 5 Divestitures for additional information.
Intangible asset amortization expense over the remainder of 2023 and for the years ending December 31, 2024 through 2027 is estimated to be as follows:
(In millions)
2023$1,772 
20242,274 
20252,179 
20262,124 
20271,912