Ownership	12 Months Ended
Dec. 31, 2022
Disclosure Of Beneficial Ownership [abstract]
Ownership	Note 20—Ownership The following investors, or groups of affiliated investors, are known by us to beneficially own more than 5% of the Company’s outstanding ordinary shares at December 31, 2022: • T. Rowe Price Associates, Inc., USA • Entities affiliated with RA Capital Management, LLC, USA • Entities affiliated with Artisan Partners Limited Partnership, USA • Entities affiliated with FMR LLC, USA • Baker Bros. Advisors LP, USA • Entities affiliated with Wellington Management Group LLP, USA • Entities affiliated with Janus Henderson Group plc, United Kingdom The Company’s American Depository Shares are held through BNY (Nominees) Limited as nominee, of The Bank of New York Mellon, UK (as registered holder of the Company’s outstanding ADSs).

Ownership

12 Months Ended

Dec. 31, 2022

Disclosure Of Beneficial Ownership [abstract]

Note 20—Ownership

The following investors, or groups of affiliated investors, are known by us to beneficially own more than 5% of the Company’s outstanding ordinary shares at December 31, 2022:

•

T. Rowe Price Associates, Inc., USA

•

Entities affiliated with RA Capital Management, LLC, USA

•

Entities affiliated with Artisan Partners Limited Partnership, USA

•

Entities affiliated with FMR LLC, USA

•

Baker Bros. Advisors LP, USA

•

Entities affiliated with Wellington Management Group LLP, USA

•

Entities affiliated with Janus Henderson Group plc, United Kingdom

The Company’s American Depository Shares are held through BNY (Nominees) Limited as nominee, of The Bank of New York Mellon, UK (as registered holder of the Company’s outstanding ADSs).