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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended
Mar. 31, 2012
Mar. 31, 2011
Revenue:    
Royalties $ 62,043 $ 59,235
Contract revenue 820 3,292
Total revenue 62,863 62,527
Operating costs and expenses:    
Cost of revenue 7,163 3,149
Research and development 38,394 23,317
Marketing, general and administrative 34,834 32,732
Costs of restatement and related legal activities 30 1,159
Gain from settlement   (6,200)
Total operating costs and expenses 80,421 54,157
Operating income (loss) (17,558) 8,370
Interest income and other income (expense), net 98 164
Interest expense (6,580) (5,988)
Interest and other income (expense), net (6,482) (5,824)
Income (loss) before income taxes (24,040) 2,546
Provision for income taxes 3,850 6,776
Net loss $ (27,890) $ (4,230)
Net loss per share:    
Basic (in dollars per share) $ (0.25) $ (0.04)
Diluted (in dollars per share) $ (0.25) $ (0.04)
Weighted average shares used in per share calculation:    
Basic (in shares) 110,358 107,613
Diluted (in shares) 110,358 107,613