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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
 3 Months Ended
Mar. 31, 2012
Mar. 31, 2011
Cash flows from operating activities:    
Net loss $ (27,890) $ (4,230)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 6,726 7,290
Depreciation 3,099 2,803
Amortization of intangible assets 7,616 1,979
Non-cash interest expense and amortization of convertible debt issuance costs 3,510 3,016
Deferred tax benefit   (46)
Change in assets and liabilities, net of effects of acquisition:    
Accounts receivable 298 2,211
Prepaids and other assets 4,200 (343)
Accounts payable (9,565) 4,091
Accrued salaries and benefits and other accrued liabilities 1,502 (24,502)
Accrued litigation expenses 306 684
Income taxes payable (794) 2,502
Net cash used in operating activities (10,992) (4,545)
Cash flows from investing activities:    
Acquisition of businesses, net of cash acquired (42,397)  
Purchases of property, plant and equipment (3,043) (6,478)
Acquisition of intangible assets (250)  
Purchases of marketable securities   (94,160)
Maturities of marketable securities 82,926 62,820
Net cash provided by (used in) investing activities 37,236 (37,818)
Cash flows from financing activities:    
Proceeds received from issuance of common stock under employee stock plans 63 3,263
Principal payments against lease financing obligation (3) (417)
Proceeds from landlord for tenant improvements   6,739
Payments under installment payment arrangement   (250)
Net cash provided by financing activities 60 9,335
Net (decrease) increase in cash and cash equivalents 26,304 (33,028)
Cash and cash equivalents at beginning of period 162,244 215,262
Cash and cash equivalents at end of period 188,548 182,234
Non-cash investing activities and financing activities:    
Property, plant and equipment received and accrued in accounts payable and other accrued liabilities 3,893 2,362
Non-cash obligation for property, plant and equipment 495  
Intangible assets acquired under installment payment arrangement 1,050  
Remaining purchase consideration for acquisition of business $ 3,881