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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
 3 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Cash flows from operating activities:    
Net loss $ (10,402) $ (27,890)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:    
Stock-based compensation 4,948 6,726
Depreciation 3,791 3,099
Amortization of intangible assets 7,040 7,616
Non-cash interest expense and amortization of convertible debt issuance costs 4,089 3,510
Deferred tax benefit 263 0
Non-cash restructuring 653 0
Gain on sale of assets (1,282) 0
Change in operating assets and liabilities, net of effects of acquisitions:    
Accounts receivable 469 298
Prepaid expenses and other assets 2,965 4,200
Accounts payable (2,243) (9,565)
Accrued salaries and benefits and other accrued liabilities 4,209 1,502
Accrued litigation expenses 434 306
Income taxes payable 378 (794)
Net cash provided by (used in) operating activities 15,312 (10,992)
Cash flows from investing activities:    
Purchases of property, plant and equipment (3,703) (3,043)
Acquisition of intangible assets (1,875) (250)
Purchases of marketable securities (36,699) 0
Maturities of marketable securities 33,250 82,926
Proceeds from sale of assets 2,000 0
Acquisition of business, net of cash acquired 0 (42,397)
Net cash provided by (used in) investing activities (7,027) 37,236
Cash flows from financing activities:    
Payments under installment payment arrangement (28) 0
Principal payments against lease financing obligation (26) (3)
Proceeds received from issuance of common stock under employee stock plans 0 63
Net cash provided by (used in) financing activities (54) 60
Net increase in cash and cash equivalents 8,231 26,304
Cash and cash equivalents at beginning of period 148,984 162,244
Cash and cash equivalents at end of period 157,215 188,548
Non-cash investing and financing activities during the period:    
Property, plant and equipment received and accrued in accounts payable and other accrued liabilities 166 3,893
Non-cash obligation for property, plant and equipment 0 495
Intangible assets acquired under installment payment arrangement 0 1,050
Remaining purchase consideration for acquisition of business $ 0 $ 3,881