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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
 6 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Cash flows from operating activities:    
Net loss $ (18,246) $ (60,106)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:    
Stock-based compensation 8,522 12,941
Depreciation 7,671 6,368
Amortization of intangible assets 14,037 15,559
Non-cash interest expense and amortization of convertible debt issuance costs 8,234 7,067
Impairment of investment in non-marketable equity security 1,400 0
Deferred tax benefit 875 0
Non-cash restructuring 653 0
Gain from sale of intellectual property (1,388) 0
Change in operating assets and liabilities, net of effects of acquisitions:    
Accounts receivable (474) 913
Prepaid expenses and other assets 3,163 5,108
Accounts payable (865) (8,490)
Accrued salaries and benefits and other accrued liabilities (10,816) (8,666)
Accrued litigation expenses (8,149) (641)
Income taxes payable 544 (689)
Net cash provided by (used in) operating activities 5,161 (30,636)
Cash flows from investing activities:    
Purchases of property, plant and equipment (5,309) (8,348)
Acquisition of intangible assets (2,500) (1,625)
Purchases of marketable securities (60,496) (49,642)
Maturities of marketable securities 64,250 125,836
Proceeds from sale of intellectual property 2,250 0
Acquisition of businesses, net of cash acquired 0 (46,278)
Net cash provided by (used in) investing activities (1,805) 19,943
Cash flows from financing activities:    
Proceeds received from issuance of common stock under employee stock plans 3,054 1,170
Principal payments against lease financing obligation (62) (16)
Payments under installment payment arrangement (56) (121)
Net cash provided by financing activities 2,936 1,033
Net increase (decrease) in cash and cash equivalents 6,292 (9,660)
Cash and cash equivalents at beginning of period 148,984 162,244
Cash and cash equivalents at end of period 155,276 152,584
Non-cash investing and financing activities during the period:    
Property, plant and equipment received and accrued in accounts payable and other accrued liabilities 112 3,762
Non-cash obligation for property, plant and equipment $ 0 $ 2,008