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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Revenue:      
Royalties $ 264,614 $ 262,415 $ 271,521
Contract and other revenue 71,983 33,863 25,037
Total revenue 336,597 296,278 296,558
Operating costs and expenses:      
Cost of revenue [1] 67,090 45,344 41,947
Research and development [1] 129,844 111,110 110,025
Sales, general and administrative [1] 95,145 70,554 74,770
Restructuring charges 0 3,576 39
Impairment of in-process research and development intangible asset 18,300 0 0
Change in contingent consideration liability (6,845) 0 0
Gain from sale of intellectual property 0 (3,686) (3,529)
Gain from settlement (579) (2,040) (2,040)
Total operating costs and expenses 302,955 224,858 221,212
Operating income (loss) 33,642 71,420 75,346
Interest income (expense), net 1,740 1,224 (276)
Interest expense (12,745) (12,413) (24,820)
Interest and other income (expense), net (11,005) (11,189) (25,096)
Income before income taxes 22,637 60,231 50,250
Provision for (benefit from) income taxes 15,817 (151,157) 24,049
Net income $ 6,820 $ 211,388 $ 26,201
Net income per share:      
Basic (in dollars per share) $ 0.06 $ 1.84 $ 0.23
Diluted (in dollars per share) $ 0.06 $ 1.80 $ 0.22
Weighted average shares used in per share calculations:      
Basic (in shares) 110,162 114,814 114,318
Diluted (in shares) 113,140 117,484 117,624
[1] * Includes stock-based compensation: Cost of revenue$56 $63 $44Research and development$9,165 $6,762 $7,216Sales, general and administrative$11,792 $8,271 $7,470