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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Revenue:    
Royalties $ 68,956 $ 62,877
Contract and other revenue 28,395 9,805
Total revenue 97,351 72,682
Operating costs and expenses:    
Cost of revenue [1] 19,731 12,207
Research and development [1] 36,000 28,527
Sales, general and administrative [1] 28,186 23,095
Gain from settlement 0 (441)
Total operating costs and expenses 83,917 63,388
Operating income (loss) 13,434 9,294
Interest income and other income (expense), net 154 242
Interest expense (3,206) (3,141)
Interest and other income (expense), net (3,052) (2,899)
Income before income taxes 10,382 6,395
Provision for (benefit from) income taxes 7,376 4,517
Net Income (Loss) $ 3,006 $ 1,878
Net income per share:    
Earnings Per Share, Basic $ 0.03 $ 0.02
Earnings Per Share, Diluted $ 0.03 $ 0.02
Weighted average shares used in per share calculation:    
Basic (in shares) 111,464 109,733
Diluted (in shares) 115,325 112,252
[1] Includes stock-based compensation